New treatments compared to established treatments in randomized trials
نویسندگان
چکیده
منابع مشابه
New treatments compared to established treatments in randomized trials.
BACKGROUND The proportion of proposed new treatments that are 'successful' is of ethical, scientific, and public importance. We investigated how often new, experimental treatments evaluated in randomized controlled trials (RCTs) are superior to established treatments. OBJECTIVES Our main question was: "On average how often are new treatments more effective, equally effective or less effective...
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BACKGROUND Blinding is a cornerstone of treatment evaluation. Blinding is more difficult to obtain in trials assessing nonpharmacological treatment and frequently relies on "creative" (nonstandard) methods. The purpose of this study was to systematically describe the strategies used to obtain blinding in a sample of randomized controlled trials of nonpharmacological treatment. METHODS AND FIN...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2012
ISSN: 1465-1858
DOI: 10.1002/14651858.mr000024.pub3